The state of genetics and molecular biology in 2020, in light of the decree by the President of the Russian Federation, Vladimir Putin, on November 28, 2018. № 680 “On the development of genetic technology in the Russian Federation”
Despite indisputable achievements, the current understanding of genetics and molecular biology has important gaps. First of all, in the basic design, in the genetic coding model of M. Nirenberg and F. Crick. The model is unfinished in the following three strategic areas, which will have a negative impact on the implementation of the presidential decree.
1st area: Misunderstanding of the role of the 3rd nucleotide in non-synonymic codons
which is expressed during protein synthesis. This role switches the genetic code of proteins to a level of speech and meaning, which opens up endless possibilities for creating protein codes that make sense. They have a linguistic and mental nature:
2nd area: Insufficient understanding of biomorphogenesis, including the post-embryonic one. The biomorphogenesis strategy is defined by quantum acts of non-locality and spatio-temporal acts of bioholography.
A theoretical work of this nature made it possible to create an apparatus and a methodology, allowing the production of wave laser processes imitating Nature, which made possible the regeneration of the pancreas, teeth, retina, spinal cord, trophic pressure ulcers ("diabetic foot" syndrome), burning and frostbite.
Some useful links:
- Interview with P. Garayev in London after his presentation at the International Conference on the genesis of Consciousness: https://vimeo.com/362114843 ( password to view: adaconde)
- Interview with P. Garayev for Central Television: https://youtu.be/quSa8Gh512wvs/c/
- Garayev P.P., Vlassov G.P., Poltavtseva R.A., Volochine L.L., Leonova Garayeva E.A. Attempt to regenerate the dog's tooth using the method of a new direction in biology ‒ Linguistic ‒ Wave Genetics. Institute of Quantum Genetics (LLC), Russia. Received: July 30, 2018 | Published: October 11,2018
- https://wavegenetics.org/researches/vliyanie-modulirovannogo-biostrukturami elektromagnitnogo-izlucheniya-na-techenie-alloksanovogo-saharnogo-diabeta-u-kryis
3rd area: Genetic information (genes) is dual. This position that has been affirmed, was proposed by A. G. Gurvitch in 1924, who said that chromosomes had a wave equivalent. It was only today that we have got experimental confirmation of this:
Our functional gene transmission laser technologies are based on this experimental fact, which was independently confirmed by the group led by French Nobel Prize winner, Luc Montagnier [arXiv: 1012.5166v1 [q-bio.OT] 23 Dec 2010]. It means that the methodology of working with the genome can be built on a different simpler basis. In other words, it is possible to work WITHOUT using DNA material and other basic metabolites. Just work with their wave equivalents. This will simplify and speed up the work of several orders of magnitude.
A word about CRISPR-Cas technology, which is globally considered to be the foundation of work on the human genome and other biological systems. The concept of looking for dangerous genes or mutations, and their eradication using CRISPR-Cas technology can and should be replaced by the simple and clear logic of the linguistic wave model that imitates Nature, to work on the genome. By this process it becomes possible to program any cell, including stem cells, thus as whole organisms, by transmitting dynamic wave signals to them, as control and transformation vectors of their metabolomes within the metabolism of our choice. The main drawback of the CRISPR-Cas technology is not using linguistic and wave components of the genome, while searching for targets upon which to act. Cas-nuclease is based on the dogma of molecular biology of recognising complementary and close pairs A-T and G-C (at Angström level), as established by Watson and Crick. In reality, these interactions must be preceded by a distant interaction-recognition, TARGETED ferment-substrate, wave. It is what is imposed by our programs as part of the effects of working on the quantum genome and protein synthesis system. (See references in our publications).
The lack of this understanding among geneticists and biochemists leads to unintended negative results, so-called "off target" effects, when Cas-nucleases cut collateral genes to those planned. This probably happens during the reading of non-target genes, following wave recognition of the wrong target sites on these genes, which are irrelevant to the work in progress. Such disadvantages are absent from our laser technologies which simulate the informational events of the genome, imitating Nature. The immune system of bacteria (the basis of CRISPR-cas technology) and that of the Human Being are noticeably distinct. The reductionist idea of reducing the genome human to that of bacteria, in CRISPR-Cas technology, is anti-productive and leads to anomalies in their work.
Taken together, genetics and molecular biology need a transpositional leap of theoretical and experimental to move to a dualist understanding of the Vital Activity, that is to say in the understanding of how the genome functions, and the metabolome as a whole, from the point of view of linguistics and waves. This does not exclude traditional representations of that, but it enhances them. For the moment this slowed down transformation, without official support, begins to obtain practical results now that surpass by far the traditional strategic goals of genetics and biology molecular.
In view of the supporting documents listed, it makes sense to plan for the next step, taking a look at the road traveled by genetics, and taking into account the Decree of the President of the Russian Federation dated 11/28/2018, No. 680, “From development of genetic technologies, including genetic technologies genetic composition, the creation of scientific and technological incubators for medicine and agriculture ". The development prospects of this huge program are considerable, but they require a certain maturation. Especially since one of the major keys to its achievement is CRISPR-Cas technology, mentioned above, which has the defect of creating deviant, negative, target-off effects. But that's not the point. This is the incomplete understanding of the strategic functioning of genome mechanisms. The center of such technologies could develop the spintronics effects in chemical and physicochemical processes. This route was opened by the Russian academician Anatole Boutchatchev, for the conduct of reactions chemicals using the reorientation of the spins of atomic nuclei and electrons in materials participating in chemical and physicochemical processes. He was nominated for the Nobel Prize for having developed this path.
On the other hand, research has emerged on similar processes during use of nucleotides as the basis and structure of genes.
Our focus for the laser programming interaction of the genomes of biological systems is exactly related to the transformation of collective spin states of genetic significance; laser photons which scan the structures biological and which act on living cells, creating spintronic vectors for piloting genomes and metabolomes (See our publications above). These works are firsts and they will develop. And, as I have already indicated, they are already bringing perceptible results in principle, and in practice, and they have lasted since 1984 despite obstructions.
This proves that the strategy of working with organizations, that is proposed, is just.
Taking this into account, it can be assumed that the following themes of the Institute
of Gene Biology:
1- the mechanisms for maintaining the stability of the genome,
2- the study of the operating mechanisms of the CRISPR system / Case of the bacterial defense against foreign DNA,
3- research and development of new biosynthetic and anti-bacterial,
4- development of production technologies for transgenic organisms and cell lines,
5- creation in vivo of rare disease models, using technologies of genomic editing,
with the aim of researching therapeutic avenues personalized or target-oriented, can be supported and developed using Genetic Wave Linguistic technologies, which we offer.
Garaïev P. P., Doctor of Biological Sciences,
Member of the New York Academy of Sciences,
Academician of the Russian Academy of Sciences, ..
Director of the "Biokvant" scientific center.